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For over 60 years, we thought metformin worked mainly through the liver and gut. But new research suggests the brain may play a major role too. This study identified a specific brain pathway (Rap1 in the hypothalamus) that appears critical to metformin’s glucose-lowering effects, potentially reshaping how we understand one of the world’s most prescribed diabetes medications. Source: Sci. Adv. 2025;11:eadu3700
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This client came in with Grade II fatty liver, started treatment and followed instructions carefully. After 3 weeks, the repeat scan now shows mild fatty liver Your liver may be quiet, but when it starts getting stressed, the body will eventually speak. Constant tiredness, heaviness, poor digestion, abdominal discomfort, excess alcohol, unhealthy eating, and drug abuse can all put pressure on the liver. Early attention matters. Don’t wait until the damage becomes serious before taking your healt
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