The CD40–CD40L costimulatory pathway regulates adaptive and innate immune responses and has been implicated in the pathogenesis of multiple sclerosis. Frexalimab is a second-generation anti-CD40L ...
What Is Late-Onset Multiple Sclerosis? When you have multiple sclerosis (MS), your immune system attacks nerve cells and fibers called axons in your brain. When this happens, your brain can’t send ...