CHAMPAIGN, Ill. — A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination ...

"As in our model, we also consider the enzyme dynamics and coupling, we go beyond this existing concept, considering two reaction coordinates," says Michalis Chatzittofi, first author of the study.

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

A research team led by Associate Professor Shinpei Yamaguchi and the late Professor Masako Tada of the Faculty of Science, together with Professor Yojiro Anzai and Lecturer Yohei Iizaka of the Faculty ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...