Liver cells are indispensable for research—for drug testing, to better understand diseases such as hepatitis, fatty liver, cirrhosis, or liver cancer and for development of future cell therapies.

To overcome these limitations, the research team developed a "targeted RNA acetylation system (dCas13-eNAT10)" by combining Cas13, gene scissors that precisely target desired RNA, with a hyperactive ...

Two separate research teams used base editing to make single-nucleotide changes in human embryos this month, targeting genes ...

Nanoparticles are widely used in medicine to deliver drugs, genes or imaging agents to specific parts of the body. Once a ...

Gene editing has emerged as a powerful approach for targeting the genetic causes of disease, yet delivering the editing machinery into the correct cells efficiently, safely, and at the scale needed ...

CRISPR functions as a programmable genetic memory system derived from bacterial immune defenses against viral infections. Guide RNA allows for rapid multiplexed targeting compared to older ...

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, ...

A new gene-editing technique enables the correction of multiple genetic mutations simultaneously, transforming the prospects for millions living with complex inherited diseases, such as cystic ...

India has brought cell/stem-cell therapies, gene therapies and xenografts under CLAA oversight, requiring central and state approval to boost safety, uniform standards and regulation of advanced ...

On Monday morning in New Orleans, 23-year-old Daniel Cressy rang a bell inside Manning Family Children’s hospital and stepped ...